Inhibitory Effect of Photodynamic Therapy with a Novel Indocyanine Green-labeled Nanoparticle and Near-infrared Light on the Growth of Bone Metastasis of a Human Breast Cancer in vivo
نویسندگان
چکیده
Toshinori Tsukanishi, Masataka Sakane, Tetsuya Abe, Toru Funayama, Shinzo Onishi, Eiichi Ozeki, Isao Hara, Masashi Yamazaki. Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan, Department of Orthopaedic Surgery, University of Tsukuba, Tsukuba, Japan, Department of Orthopaedic Surgery, Takahagi Kyodo Hospital, Kempoku Medical Center, Takahagi, Japan, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan.
منابع مشابه
Photosensitivity and Radiosensitivity of Indocyanine Green on Human Cell Lines MCF7 and DFW
Background & Aims: In this study with the aim of benefiting from non-laser sources in photodynamic therapy, photo and radio sensitivity of indocyanine green as a sensitizer in photodynamic and radiation therapies were investigated. Methods: Based on the broad absorption peak of indocyanine green and using non-coherent light, the experiments were performed on human cells derived from breast canc...
متن کاملAnti-cancer and anti-immunomodulatory properties of novel Arteether in Folic acid-Chitosan-Fe3O4 composite nanoparticle for treatment of breast cancer
Goal: The potent anti-cancer activity of Arteether (ARE) has been the focus of many studies. However, the hydrophobic property of this drug limits its application. To increase the bioavailability of ARE, we formulated a nanosystem (NS) of folic acid (FA), chitosan (CS) and Fe3O4 for delivery of ARE against breast cancer. Material and Methods: The CS coated Fe3O4 was synthesized by co-precipitat...
متن کاملPhotodynamic therapy (PDT)
Photodynamic therapy (PDT) is a comparatively novel therapeutic method involving a safe light source and a light-sensitive substance, termed as photosensitizers (PSs), such as methylene blue (MB), toluidine blue (TBO), sulfonated aluminum phthalocyanine, chlorine derivatives, nontoxic indocyanine green (ICG), and curcumin (CUR). (1) The combination of a nontoxic PS with low-intensity visible li...
متن کاملمقایسه اثر دو منبع نور لیزری متفاوت بر بازده درمان فتودینامیکی سرطان پستان در شرایط برون تنی
Background and Objective: Photodynamic therapy is a new therapeutic modality for the treatment of cancer. Photodynamic therapy uses an inactive drug and a light source to activate the drug to produce reactive oxygen species that destroy the cancer cells. In the present study, the effect of two different laser light sources on the efficiency of photodynamic therapy was evaluated using a breast c...
متن کاملChange of Hemoglobin Concentration with nano particles can predict breast cancer using near infrared source?
Introduction: Early detection and treatment of breast cancer may be helping to save the lives of patients. Many new techniques have been urban to detect breast cancer. One of them is the use of nano-particles for accuracy and early diagnosis after photo transfer. In this study, rod gold nano particles was used according their ability to change light source transfer intensity. ...
متن کامل